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Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) 是羧甲基纖維素的鈉鹽,經(jīng)常用作粘稠劑,糊劑和阻隔劑。
生物活性
Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
體內(nèi)研究(In Vivo)
Protocal for preparing 0.5% CMC-Na Solution
Measure 0.5g of dry CMC-Na and dissolved in 100 ml ddH2O/0.9% Saline (0.9 g NaCl in 100 ml ddH2O) to make a clear solution.
Under the condition of stirring and heating (50-65°C), adding CMC-Na slowly to ddH2O/0.9% Saline helps to accelerate dissolution.
Note
1.You must ensure that your CMC-Na solution does not exist solid-liquid separation phenomenon. The solution is in a uniform and transparent state has no particles in it.
2.Completely dissolution of CMC-Na may requires 4 hours or more longer.
In a pharmacological test, CMC-Na (oral;5% in water; 1 year) is well tolerated in rats[2].
In an acute oral toxicity study in female mice, LD50 of CMC-Na for female mice is 14 g/kg body weight of mice, equivalent to 9.8 g/kg body weight of rat, categorized as practically non-toxic according to Loomis criteria (LD50 5-15g/kg body weight of rat)[3].
CAS 號(hào):9004-32-4
中文名稱(chēng):羧甲基纖維素鈉5000-15000
運(yùn)輸條件:Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years |
參考文獻(xiàn)
Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) 是羧甲基纖維素的鈉鹽,經(jīng)常用作粘稠劑,糊劑和阻隔劑。
生物活性
Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
體內(nèi)研究(In Vivo)
Protocal for preparing 0.5% CMC-Na Solution
Measure 0.5g of dry CMC-Na and dissolved in 100 ml ddH2O/0.9% Saline (0.9 g NaCl in 100 ml ddH2O) to make a clear solution.
Under the condition of stirring and heating (50-65°C), adding CMC-Na slowly to ddH2O/0.9% Saline helps to accelerate dissolution.
Note
1.You must ensure that your CMC-Na solution does not exist solid-liquid separation phenomenon. The solution is in a uniform and transparent state has no particles in it.
2.Completely dissolution of CMC-Na may requires 4 hours or more longer.
In a pharmacological test, CMC-Na (oral;5% in water; 1 year) is well tolerated in rats[2].
In an acute oral toxicity study in female mice, LD50 of CMC-Na for female mice is 14 g/kg body weight of mice, equivalent to 9.8 g/kg body weight of rat, categorized as practically non-toxic according to Loomis criteria (LD50 5-15g/kg body weight of rat)[3].
CAS 號(hào):9004-32-4
中文名稱(chēng):羧甲基纖維素鈉5000-15000
運(yùn)輸條件:Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years |
參考文獻(xiàn)